http://www.aplsc.org/
Animal Protection League of South Carolina

http://www.arfsc.homestead.com/
The Animal Rescue Fund of South Carolina. Seneca

http://www.cbhr.com/
Carolina Basset Hound Rescue (CBHR) is a volunteer-staffed, non-profit organization rescuing and placing stray, unwanted, neglected, and abandoned basset hounds in permanent homes.

http://carolinarescues.org/
Our main goal is to make this world a better place for pets by reducing the number of unwanted puppies/kittens that are born into it and by improving the lives of those that are already here.

http://www.pressenter.com/~marshaha/critter.htm
Critter Connection

http://www.greenvillehumane.com/
The Greenville Humane Society has served the Greenville community since the 1800’s, and continues to unite families with previously unwanted animals everyday.

http://www.hhhumane.org/
The Hilton Head Humane Association

http://www.jaspca.com/
John Ancrum SPCA. Charleston

http://www.pethelpers.org/
Pet Helpers Adoption Center. Charleston

http://www.petsinc.org/
PETS, Inc. has developed programs to address the problems from the point of rescue, through the rehabilitation and adoption processes and then, going a step further, to insure the animal has a reasonably good chance for successful integration into the family  by addressing its training and emotional needs.

http://www.netpets.org/netp/foster.php/
A NationWide & Global network of Individual Foster Homes that will house, nurture and care for the dogs, cats, birds, horses and all other pets for all the Military personnel Only.

http://www.projectpet.com/
Project Pet is a 501(c)(3) community-based, people/pet project founded by volunteers from four local animal welfare organizations who have joined together to humanely reduce pet overpopulation in the Midlands through innovative, pro-active programs.

http://www.spartanburghumanesociety.com/
Spartanburg Humane Society

http://www.geocities.com/Godscritters/
St. Frances Humane Society. Georgetown

http://www.dogdata.com/
We are a private, not-for-profit, no-kill, dog shelter, taking in
abandoned and abused dogs in the Myrtle Beach, SC area for 9 years, solely supported by myself. I need help now. I need volunteers to help with adoptions, foster homes, fundraising, donations, events, organizing, media, graphics, grants, picking up dog food and donated
items.